Which CVS Locations Are Closing in 2025? Here’s What We Know

How Many CVS Stores Were Scheduled to Close in 2025?

The most authoritative number comes from CVS Health’s annual report. According to the filing, the company conducted a strategic review of its retail business during the third quarter of 2024 and decided to close 271 additional stores in 2025.

That figure was separate from the earlier program announced in 2021, when CVS said it would close roughly 900 stores over three years beginning in 2022. The original strategy aimed to reduce overlapping locations while introducing a mixture of traditional pharmacies, health-focused stores, and new retail formats.

Which CVS Locations Were Reported Closing in 2025?

At least 39 locations across 17 states and Washington, D.C., were publicly identified during the first half of the year. Some had already closed when they were reported, while others had announced closing dates. The following addresses were among the most widely documented locations.

Alabama

• 2901 Morgan Road, Bessemer
• 3303 Clairmont Avenue, Birmingham

California

• 499 Haight Street, San Francisco
• 1701 K Street, Sacramento

Florida

• 3090 South Monroe Street, Tallahassee
• 13300 East Colonial Drive, Orlando
• 2201 Edgewater Drive, Orlando

Georgia

• 439 Highland Boulevard, Atlanta

Illinois

• 8639 South Cicero Avenue, Chicago
• 401 West Armitage Avenue, Chicago
• 2000 Skokie Valley Road, Highland Park

Indiana

• 9550 Allisonville Road, Indianapolis

Iowa

• 2420 Lincoln Way, Ames
• 215 Euclid Avenue, Des Moines

Maryland

• 1000 South Charles Street, Federal Hill, Baltimore
• 7235 Wisconsin Avenue, Bethesda
• 34 North Cannon Avenue, Hagerstown

Massachusetts

• 55 Summer Street, Boston

Michigan

• 28774 Gratiot Avenue, Roseville
• 27700 Harper Avenue, St. Clair Shores

Missouri

• 2435 Independence Avenue, Kansas City
• 4531 Troost Avenue, Kansas City
• 9433 Manchester Road, St. Louis

New York

• 955 Payne Avenue, North Tonawanda
• 153 Central Avenue, Albany
• 1026 Madison Avenue, Albany
• 1241 Lexington Avenue, New York City
• 1654 Richmond Avenue, Staten Island

North Carolina

• 201 West Fourth Street, Winston-Salem

Ohio

• 10825 Kinsman Road, Cleveland

Pennsylvania

• 125 East Main Street, Plymouth

Texas

• 3890 Phelan Boulevard, Beaumont

Virginia

• 10390 Willard Way, Fairfax

Washington, D.C.

• 1117 10th Street NW
• 1100 Fourth Street SW
• 400 Massachusetts Avenue NW
• 1515 New York Avenue NE, inside Target
• 4500 Wisconsin Avenue NW, inside Target
• 7828 Georgia Avenue NW, inside Target

Additional closures were reported later in the year, including locations that did not appear in the early national compilations. For example, regional business coverage identified a CVS at 8585 Elk Grove Boulevard in Elk Grove, California, while other local reports documented further closures in Maryland, Alabama, New York, Missouri, and the Washington metropolitan area.

Why Was CVS Closing More Stores?

Too Many Stores in the Same Market

CVS expanded aggressively for decades, sometimes ending up with several pharmacies located only a few miles apart. That arrangement can be convenient for customers, but it also means multiple leases, utility bills, inventories, and staffing schedules competing for the same neighborhood prescriptions.

When one store can absorb most of the prescriptions from another nearby location, closing the weaker site may appear financially logical. In Beaumont, Texas, for example, customers at the closing Phelan Boulevard store were directed to another CVS approximately two miles away.

Population and Shopping Habits Have Changed

CVS said its decisions considered population shifts, consumer purchasing patterns, store and pharmacy density, access to pharmacy care, and the health needs of individual communities. In plain English, the company was studying where people live, how they shop, and whether one neighborhood had more CVS signs than traffic lights.

Customers increasingly refill prescriptions through mobile apps, use delivery services, buy household goods online, and visit stores less frequently for general merchandise. These changes do not eliminate the need for pharmacists, but they can reduce revenue from the “front store,” where CVS sells beauty products, snacks, seasonal goods, and over-the-counter medications.

CVS Was Pursuing Major Cost Savings

The closures were also connected to a larger restructuring program intended to simplify operations, improve efficiency, and reduce costs. CVS had identified a multiyear opportunity to generate approximately $2 billion in savings through several measures, including organizational changes and adjustments to its physical store network.

That does not necessarily mean every closing store was losing money. Retail decisions can also involve expiring leases, nearby store capacity, long-term property costs, local competition, and whether a location fits the company’s future healthcare strategy.

Did CVS Close Every Store on the Reported List?

The addresses above were reported as closed, scheduled to close, or affected during the 2025 restructuring. Still, readers should be cautious when using older closure lists. Plans can change, closing dates can move, and pharmacies inside Target stores may be treated differently from full-size standalone CVS locations.

CVS’s own store locator, the CVS mobile app, and direct communication with the local pharmacy remain the best ways to verify whether a particular store is operating. Customers should also distinguish between a permanently closed location and a store that is temporarily unavailable because of weather, staffing, construction, or modified pharmacy hours.

National coverage repeatedly noted that CVS declined to provide a complete list of the 271 stores. That means headlines promising the “full CVS closing list” should be approached with the same healthy suspicion one might reserve for a coupon that says “up to 90% off.” Technically possible, perhaps, but the fine print matters.

What Happens to Prescriptions When a CVS Closes?

When a pharmacy closes, prescriptions are generally transferred to another nearby CVS unless the customer makes a different arrangement. The destination store is often identified through letters, emails, text messages, signs at the closing location, or notices attached to prescription materials.

At the Federal Hill CVS in Baltimore, which was scheduled to close on April 2, 2025, prescriptions were transferred to a CVS on East Pratt Street about a mile away. Employees at the Federal Hill location were reportedly offered comparable roles elsewhere within the company. In Beaumont, customers were directed to the CVS on College Street after the Phelan Boulevard store closed.

Customers are not required to keep their prescriptions with CVS. A patient may request a transfer to another CVS, an independent pharmacy, a supermarket pharmacy, or another chain. Controlled substances and prescriptions without remaining refills may require additional assistance from the prescribing physician.

Steps Customers Should Take Before a Closing Date

• Confirm which pharmacy will receive active prescriptions.
• Refill essential medications before the final week when appropriate.
• Update doctors, caregivers, and family members with the new pharmacy information.
• Check whether the new location participates in the same insurance network.
• Ask how automatic refills, vaccine appointments, and specialty medications will be handled.
• Download or print an updated medication list for personal records.

A little preparation can prevent the unfortunate experience of discovering that an urgent prescription has moved across town while you are already wearing pajamas and feeling terrible.

Will CVS Open Any New Stores?

Yes. The 2025 strategy was not simply a retreat from physical pharmacies. CVS said it planned to open approximately 30 new pharmacy locations during the year, including pharmacies inside Target stores. The company also introduced smaller, pharmacy-focused formats in selected communities.

These smaller locations emphasize prescriptions, vaccinations, medication support, and a curated assortment of essential health products rather than aisle after aisle of seasonal decorations and family-size candy. CVS said the approach was designed to place the right type of pharmacy in each community instead of relying on one standard store model everywhere.

The company reported that it continued to operate more than 9,000 pharmacy locations and that more than 85% of Americans lived within 10 miles of a CVS Pharmacy. That national statistic sounds reassuring, but it does not fully describe local access. Ten miles in a suburban area with a car is very different from ten miles for an older adult who depends on public transportation.

How the CVS Closures Fit Into the Changing Pharmacy Industry

CVS was not the only major drugstore chain reducing its footprint. Traditional pharmacies were facing pressure from online prescription delivery, supermarket pharmacies, big-box retailers, higher operating expenses, reimbursement challenges, and changing consumer expectations.

The modern pharmacy is being asked to perform two difficult roles at once. It must operate as a healthcare destination where patients can consult trained professionals, receive vaccines, and manage complicated medications. At the same time, it must function as a profitable retail store selling shampoo, batteries, snacks, and a suspicious number of stuffed animals before Valentine’s Day.

Digital services may improve convenience for routine refills, but physical pharmacies remain especially important for urgent prescriptions, vaccinations, medication counseling, and patients who have limited internet access. Fewer stores can mean longer drives, heavier workloads at surviving pharmacies, and longer lines during busy periods.

Real-World Experiences When a Neighborhood CVS Closes

A store closure may look like a simple address change on a corporate spreadsheet. For customers, however, the experience can involve a surprising number of small disruptions.

The Routine Prescription Customer

Consider someone who picks up blood pressure medication from the same CVS every month. The pharmacist recognizes the customer, the store is on the route home from work, and the prescription history is already in the system. When that location closes, the prescription may transfer automatically, but the familiar routine disappears.

The replacement pharmacy could be only two miles away, yet those two miles may add another traffic light, a difficult parking lot, or a bus transfer. The new store may also be busier because it has absorbed hundreds of additional prescriptions from the closed branch. What used to be a five-minute stop can become a 30-minute expedition starring a crowded pickup line and one deeply exhausted pharmacist.

The Parent Managing Several Medications

Parents may experience the transition differently. A household might have one child using an inhaler, another taking antibiotics, and an adult waiting for an insurance authorization. If all prescriptions transfer cleanly, the change is mostly an inconvenience. If one medication remains at the old location or an automatic refill is interrupted, the parent may need to call the pharmacy, physician, and insurance company.

The best approach is to verify each family member’s medication separately. Customers should not assume that every prescription, refill request, or vaccine appointment moved simply because one did. Pharmacy systems are powerful, but they are not magical creatures that organize every detail while everyone sleeps.

The Older Adult Without Reliable Transportation

Older adults and people with disabilities can face more serious consequences. A nearby CVS may have been reachable on foot, through a senior transportation program, or with help from a neighbor. A replacement location several miles farther away could require new arrangements.

In these situations, customers can ask whether the receiving pharmacy offers delivery, whether their insurance provides mail-order options, or whether an independent pharmacy is located closer. The nearest CVS is not automatically the only choice, and a locally owned pharmacy may offer services such as synchronized refills or personal delivery.

The Employee Experience

Store employees also live through the transition. Some may be offered positions at nearby CVS locations, as reported during the Federal Hill closure in Baltimore. Even when another job is available, the new assignment can change commuting time, work schedules, responsibilities, and relationships with regular customers.

Pharmacy technicians and pharmacists at receiving stores may face a sudden increase in prescription volume. Customers who encounter longer waits should remember that the person behind the counter probably did not personally design the national restructuring plan between lunch and the 2 p.m. vaccination appointment.

The Final Week Before Closing

The last days of a pharmacy can feel confusing. Shelves may become sparse, merchandise may be marked down, and signs may direct customers to another location. Some people arrive unaware that the store is closing. Others know about the closure but assume the pharmacy will remain open until the retail section shuts its doors.

Customers should avoid waiting until the final day to resolve medication questions. Calling early, confirming the receiving pharmacy, and requesting necessary refills can reduce stress. It is also sensible to save the new pharmacy’s phone number and address rather than trusting memory during the next medical emergency.

For many people, the emotional reaction is not really about losing a place to buy cough drops. It is about losing a familiar healthcare connection. A neighborhood pharmacist may have answered years of questions, caught potential medication conflicts, or helped a family navigate insurance problems. The replacement store may provide excellent care, but trust and familiarity take time to rebuild.

How to Check Whether Your Local CVS Closed

Because no complete official list was released, customers should verify local information directly. Search for the store in the CVS locator or mobile app, call the pharmacy, and look for notices posted at the entrance. Google and Apple Maps can be useful, but their business information may not update immediately after a closure.

Customers with automatic refills should log in to their CVS account and confirm the selected pharmacy. Anyone who uses MinuteClinic, receives specialty medications, or has a scheduled vaccination should verify those services separately because the replacement store may not offer exactly the same features.

Conclusion

CVS Health’s official plan called for 271 retail store closures in 2025, following approximately 900 closures completed between 2022 and 2024. The company described the reductions as a strategic effort to match its pharmacy network with population trends, shopping behavior, healthcare access, and community needs.

The publicly reported addresses provide useful guidance, but they do not represent a complete official list. Customers should confirm the status of their local CVS and check where prescriptions, appointments, and automatic refills have been transferred.

CVS is not abandoning neighborhood pharmacy care altogether. It is experimenting with smaller stores, pharmacies inside other retailers, digital services, and healthcare-focused formats. Whether that redesigned network feels more efficient or merely farther away will depend heavily on where each customer lives and how they access medication.

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